From the name A.I.D.S means aquired immune deficiency syndrome. A
syndrome is a group of symptoms that collectively indicate or characterize a disease, psychological disorder, or other
abnormal condition.
If viruses are dangerous to humans,why are they used in gene therapy? Advances in understanding and manipulating genes have set the stage for scientists to alter a person's genetic material to
fight or prevent disease. Gene therapy treatment that involves introducing genetic material (DNA or RNA) into a person's
cells to fight disease. Gene therapy is being studied in clinical trials (research studies with people) for many different
types of cancer and for other diseases.Viruses are used in the transfer of these generic materials!!!!!!!!!! Read moore
HIV and AIDS does not cause immune deficiency;immune deficiency
cause AIDS
When we talk about HIV and AIDS, most people think
it is an infection from viruses. Viruses are not the main issues when we talk about AIDS. HIVis primarily
not an infection and neither is it a disease. It is the response of the immune system to antigens, dietary assaults, and toxins
that constitute the pain we feel and the laboratory results our doctors give us. HIV is an umbrella of conditions that result from impaired immune functions and inflammatory conditions
that had spiraled out of control. Holistic healing focus on the big picture and inflamation that ultimately carries your HIV and AIDS along.
Twenty years from now,when another epidemics is created,just
remove the name AIDS, Swine flu virus, Hepatitis C,Hepatitis B etc .You will see thesame pattern of deception and
billion of dollars allocation to CDC,NIH,WHO,UNICEF etc.At the end of the hoopla,the world's population will be reduced
by about 700,000 deaths. Then they will say there is a vaccine or cure like gonorrhea and syphillis that made penicillin
a billion dollar pill
The conventional management of infectious
microbes[viruses,parasites,bacteria etc] is anchored on Louis Pasteur’s germ theory of diseases and Charles Darwin
theory of genetic determinism (gene therapy). In his book, the origin of species, Darwin believes that our biological make
up determines our life i.e. our biology determines our biography. Like Pasteur, Charles Darwin recounted his theory at the
twilight of his life with the following statements "In my opinion, the greatest error which I have committed has been
not allowing sufficient weight to the direct action of the environments, i.e. food, climate etc independently of natural selection…when
I wrote the ‘origin’, and for some years afterwards, I could find little good evidence of direct action of the
environment; now there is a large body of evidence" .On his deathbed, Louis Pasteur- the father of the modern day germ
theory of diseases said ‘"the host is more important than the invader" .In simple english he recounted his
life long teary that germs,antibiotics and microbes as the culprit in the treatment of infections;he demphasised
the virus and emphasised the immune system
Microbes had always had a symbiotic and/or commensal
relationship with humans. They are part of the ecological chain. They are part of God’s creatures for his creations
(humans). They had always lived within and without humans.They live in our intestine where they digest
our foods and on our skins to keep them alive. Microbes clean the environment and turn grapes into wine. The Ebola virus that
had commensal relationship with animals became problematic to humans when we moved civilization to the forest. The incidence
of infectious diseases increases when humans shared habitation withanimals.
The cat and mouse/hide and seek relationship between microbes and antibiotics always turned out to
be a goose chase that leads to virulent mutantgenic strains. - A God given survival instinct that characterized all intelligent
beings that included microbes. Microbes are like fire –good servants and bad masters. Humanity will be extinct without
microbes.Millions of people with excellent
immune systems live peacefully with non- infective microbes from HIV and the common cold virus to herpes zoster. There are
no known antibiotics that wipe out viruses. Antibiotics encourage the proliferation of drug resistant microbes. Our immune
system makes them friendly neighbors. "Human technological, modern and industrial activity had brought dormant viruses
out of commensalisms –a neutral state". The assaults on the immune system changed symbiosis and commensalism to
parasitism.
In their book, Ten Lies About AIDS, Etienne De Harven and Jean-Claude Roussez point out that HIV infection is not
the cause of AIDS. Severe immune deficiencies, commonly referred to as AIDS, result from the toxicity of many recreational
drugs and of most antiretroviral medications, from the abuse of antibiotics, and certain therapeutic protocols, from inappropriate
life style, and/or from malnutrition, alone or combined.
In her book, Goodbye AIDS! Did it ever exist?,
Maria Papagiannidou-St. Pierre, a senior Greek journalist and ex-AIDS patient thought otherwise. Born in 1965, she was diagnosed
"HIV positive" in 1985. From 1995 to 2005, she was a full-blown AIDS patient, suffering horrifically from the side-effects
of the medications, and being sometimes told she had no more than a week to live. In 2006, she started the website www.hivwave.gr and married the Canadian "HIV negative" Gilles St Pierre. In 23 April 2007, she stopped taking the pills prescribed
against AIDS, became strong again, and regained the freedom we all lost in 1984. So, what had she suffered from, a deadly
hoax? She began to research what had happened to her, met many who had questioned the HIV/AIDS dogma on her way, found the
missing answers, and now wants to shout out around the world: “The elaborate AIDS construction is built on a false foundation!”
Herbs for treating viruses may directly attack
and kill, inactivate or weaken the virus. Other herbs stimulate your immune system, allowing your body to fight the virus
naturally.Other herbs may alkalize the body,increase oxygen flow and remove toxins from the body.Under these conditions,
viruses loose hands down.
Alan Cantwell, MD - "The mixing of AIDS facts and fallacies has long been apparent to researchers
like myself who are convinced that HIV did not come from Mother Nature and “species jumping,” but was most likely
introduced via contaminated vaccine experiments exclusively targeting the Black African and the American Gay community."
Dr. Hein states that when a new disease called AIDS appeared, it provided the promise of huge amounts of funding
if it proved to be transmittable. Ellison and Duesberg argue that the health establishment manipulated public perception about
the relationship between AIDS and HIV to create the appearance of a direct linkage, so as to create a new research and health-care
paradigm, one that put them at the center of the action. In reality, the vast majority of retroviruses are harmless, and AIDS
shows very different symptoms depending on the country in which it appears. African AIDS is a different beast altogether from
that which appears in Europe and the United States. This suggests that AIDS isn’t one disease but many immune system
disorders that have been lumped together under one rubric for the sake of the organizations that specialize in their treatment.
According to the authors, anytime someone tests positive for HIV and has any of over 100 symptoms, they are automatically
classified as “having AIDS.” And yet, apparently, many people who test positive for HIV stay healthy for decades.
He shows how Ellison and Duesberg present a lifestyle explanation for what causes AIDS, including drug-use,
immune-system stress, and sexual preference. This is a more sociologically-driven idea of what AIDS is than a biological explanation.
And it challenges everything we've officially been told about the disease.
He summarizes by saying
that “the information presented was an important event in my personal understanding of how scientific institutions actually
work, what drives their research, and causes them to sometimes act like witch-hunting ‘knowledge monopolies.’
If you are at all interested in the collusion between science, government health policy, and the medical establishment, you
are bound to find it provocative and challenging.’
Aloe vera, St. Johnswort, echinacea, licorice, and ginseng are just a few of the herbs used to treat
HIV/AIDS. Taking immunity-boosting herbs (such as astragalus, echinacea, and ginkgo) may help revive an ailing immune system,
and certain herbs (such as garlic) may help battle bacteria and viruses. Deglycyrrhizinated licorice can soothe the mouth
and throat ulcers that often accompany full-blown AIDS. Just remember that even if these herbs have these powers, no one yet
understands just how they work in helping AIDS or whether using them really makes a difference in the course of the disease.
Federal Court Declares AIDS Book Illegal
In
a far-reaching decision that could throw the publishing industry into turmoil, the Federal court of the Southern District
of New York has officially banned a controversial AIDS book titled "Why We Will Never Win the
War on AIDS" from being distributed - even for free - anywhere in the United States.
The verdict against the book, rendered on November 28, ended a contentious
five-day trial in which publisher Alfred S. Regnery was suing to stop publication of the book. Judge John E. Sprizzo is expected
to enter the official judgment any day now, including a permanent injunction against the book and over half a million dollars
in penalties against the book's publisher and main author, Bryan J. Ellison. The injunction will extend a restraining order that already
shut down the book's publication last week.
"As
far as I know, this is the first time in American history that the Federal government has banned a documentary book,"
said Ellison, who was clearly shaken by the decision.
Evan Tolchinsky, the attorney who represented Ellison at the trial, has taken this case without pay because of the free
speech issue. "There's no question that this decision represents a radical departure from two hundred years of American
legal tradition," he noted. "Unless this decision is overturned, more books will soon join the banned list, businesses
everywhere will suddenly find their contracts invalid, and - worst of all - the AIDS epidemic will continue to claim victims
unnecessarily."
The book is controversial
because it documents a growing scientific debate over whether the Federal government has blamed the AIDS epidemic on the wrong
cause; no charges of indecency, libel, or violation of national security have been made against the book. Instead, Regnery
justified his lawsuit against Ellison by trying to enforce a terminated contract made between Ellison and another publisher
who had refused to publish the book. Regnery himself has never published the book, nor has he taken any serious measures to
do so.
Critics accuse Regnery of illegally
reviving the contract merely to shut down the book's publication, and point out that Regnery worked for several years as a
high-ranking official in the U.S. Justice Department.
Not surprisingly, some Federal officials have openly stated they do not want the general public to learn about the AIDS
information contained in the book. The Federal government currently spends over $7 billion per year on AIDS, all directed
against HIV, the virus said to cause AIDS. The Ellison book explains why hundreds of prestigious scientists and physicians
now believe the government has blamed AIDS on the wrong cause since 1984, and it provides startling evidence for what many
of these scientists believe is the real cause of AIDS.
The book also carefully documents why the government blamed AIDS on this virus in the first place, and names the people
who designed the War on AIDS.
Widespread
distribution of the book could shake public faith in the biomedical research establishment, says Ellison, resulting in budget
cuts for numerous Federal agencies. Judge Sprizzo's decision is controversial not only for banning the book, but also for
his conduct during the entire lawsuit. Sprizzo, himself a former top official of the Justice Department, remained consistently
hostile to Ellison's defense - declaring, for example, that Ellison had no due process rights, and trying several times to
replace Ellison's attorney with another who knew little about the case.
During the trial, Sprizzo repeatedly changed the testimony of witnesses and ordered the jury to ignore
any testimony that reflected badly on Regnery's case. Sprizzo's final instructions then suddenly redefined the entire lawsuit,
thus guaranteeing the jury's verdict against the book.
Peter Duesberg, Ellison's co-author on the book, joined Regnery's side late in the lawsuit. During the trial, Duesberg
confessed that he had been contacted by Federal officials who offered him money and other inducements to suppress the information
in the book. Duesberg claimed he did not accept these offers, yet he refused to disclose the identities of the officials.
Ellison's supporters believe this case is
a turning point that will awaken and outrage the American public against big government and its abuse of power. Not only will
he appeal the decision, says Ellison, but a movement against the Public Health establishment will undoubtedly grow around
this banned book.
The lawsuit
was held in Federal court in the Southern District of New York. The case number is 95 Civ. 0157 (JES).
COCONUT OIL: FAT THAT HEALS Coconut oil is colorless oil extracted from
the flesh of coconut. Despite the benefits of coconut oil, the Food and Drug Administration recommends avoiding coconut because
it is high in saturated oil. Why has this highly-beneficial oil been so grossly misunderstood? There are lots of saturated
oils on the market; coconut is one of the few that heals, and does not kill. Coconut meat has about 8 grams of fiber per cup
and as much proteins as green beans and carrots, as well as folic acid, calcium, iron, and vitamin B1, B6, C, and E. Unlike
other dietary fats that produce body fats, coconut oil produces energy, and unlike other vegetables oils, it does not oxidize
easily because it is resistant to free radical attack. Coconut oil is a potent natural antibiotic that is effective against
HCV and HIV. It is a natural antibacterial, antiviral, anti-fungal, and anti-protozoal food.
Its
anti-microbial properties are derived from its composition of medium-chain fatty acids (MCFA). They are absent from all other
vegetable and animal oil except perm kernel oil. They are harmless to humans and deadly to viruses. The coconut oil found
in fresh coconuts has almost no anti-microbial properties but, when eaten, our bodies break it into triglycerides, monoglycerides,
and free fatty acids, which have anti-microbial properties. The most active of these are lauric acid, capric acid, and the
monoglycerides monolaurin and monocaprin. Lauric acid is also found in breast milk. It also contains caprylic acid that is
thought to be a potent antifungal agent. Lauric acid and monolaurin have the most antimicrobial effects.
Most
bacteria and viruses are lipid coated. The fatty acids that make up their outer membranes are similar to those of the coconut
oil MCFA. This similarity facilitates their attraction to the membranes of lipid-coated viruses and bacteria. MCFA of coconut
oil are smaller and can penetrate and disrupt the lipid membranes of viruses. They spill the DNA and other cellular material
of the virus open, thereby killing the virus. The host’s white blood cells then dispose of the cellular debris. Coconut
oil is absorbed directly into the liver from the gut where it deactivates the hepatitis C virus.
Coconut
oil has exciting fat-burning power because of its concentration of medium-chain triglycerides which, instead of being stored
in fat cells, are used for energy production while stimulating metabolism. Because it is a saturated fat, Americans
have been brainwashed to link all saturated fats with heart disease without knowing the difference between fats that kill
and those that heal.
Most people do not know that coconut oil has medium-chain fatty acids
that are different from the saturated fats found in meats and other dietary products. It was part of a calculated campaign
by the food-processing industries to replace tropical unprocessed oils with vegetable hydrogenated oils that are embalmed
to have eternal shelf life and stay liquid at all temperatures. While they are processed to last forever, they send humans
to early graves. The same food processing industries that discouraged the public from using coconut oil secretly isolated
and patented genetically-engineered prototypes of its most potent ingredient, lauric acid, for big profits—a classical
case of talking out of both sides of the mouth.
Doctor
Robert Gallo who discovered the HIV virus said that there is no legitimate dissent when it comes to AIDS. But there are more
than 5,000 physicians, microbiologists, journalists and activists who disagree and say that we have been misled about the
real causes of AIDS and the nature of its treatment. The mainstream media has chosen not to provide an outlet for their opinions.
In this important film, documentary filmmaker and health expert Gary Null, traveled to more than 30 countries over an eight
year period to seek them out and get their interviews. This is the first film on AIDS that brings the most compelling of their
arguments together in one place
Dr.
Null blows the lid off the wealthy AIDS industry and shows how greed and corruption have prevented any real progress in fighting
the epidemic or its underlying causes. The film challenges the entrenched notion that AIDS or HIV is an African monkey virus
that is spread sexually and can be "treated" with harmful drugs. Instead, the film considers the common underlying
conditions of the epidemic, such as malnutrition, unclean water, poverty, illness, and poor lifestyle choices. The evidence
is damning, and a clarion call to the public that the AIDS Industrial Complex is on the wrong track and has become a spending
juggernaut completely out of control.
Olive leaf extract: Nature’s antibiotic
The pharmaceutical industry has not been able to come up with a non-toxic antiviral that can engage
the viruses without endangering the individual. Olive leaf extract can! It is the most versatile non-prescription, anti-microbial
remedy Nature has provided for humanity. Unlike antibiotic plants that predate human existence, the pharmaceutical industries
produce newer anti-virals every six months because the viruses keep altering their shapes to elude the anti-virals. Lactic
acidosis is a life-threatening complication of the reverse transcriptase anti-viral drugs used in the management of hepatitis
B and C viral infections. Olive leaf extract can eradicate the hepatitis B, C, and HIV viruses with non-toxic consequences
and added side benefits. In its natural habitat, the olive leaf controls pest infestations to the extent that commensal relations
are maintained; the ecosystem remains intact and its survival are ensured. These capabilities of the olive leaf are retained
when humans consume them. While they reduce the viral load to human tolerance, they do not hamper the activities of beneficial
microbes in the human body.
Look around the base of a black walnut tree and notice that often, nothing
will grow under the tree. Black walnut trees produce a chemical called juglone, a toxin that can prevent other plants from
growing in proximity to the tree. This chemical property is why the black walnut tree is used in parasitic and microbial cleanse.
The olive tree operates along the same principle
Dr. H.E. Remis,
a virologist working for the Upjohn Pharmaceutical Company, tried to isolate oleuropein, one of the active ingredients in
the olive leaf, without success. While oleuropin was found to be virucidal against all viruses in vitro—in
the test tube—the success did not extend to in vivo—in animal—studies. In vivo, calcium
elongate, the active ingredient in olive leaf, quickly bound to proteins in the blood and rendered it ineffective against
viruses. Upjohn made a business decision to abandon the olive leaf project because they were unable to isolate the active
ingredient for in vivo use. In simple English, the pharmaceutical industry refused to continue the olive leaf
project because they could not patent a synthetic version of the natural product. In 1994, 26 years later, independent
researchers developed an extraction process that created a potent broad-spectrum olive leaf extract that is currently commercially
available.
The olive leaf extract derived from the olive leaf (Olean europea L) is a natural, non-toxic
anti-microbial remedy. It is one of Nature’s most potent virucides. Oleuropein is present throughout the whole leaf.
It gives the olive leaf its disease-resistant properties. It helps protect the tree against predators, bacteria, and insects.
It is found to inhibit the growth of every virus, bacterium, fungus, yeast, and protozoa it was tested against. It is potent
against HIV, too. When we consume the olive leaf, we acquire these resistant and protective properties of the plant.
According to Dr. Frank Shallenberger of Gardnerville, Nevada ;A-I-D-S. Four
simple letters that when combined stir up feelings of fear, depression and ultimately, death. The definition of AIDS (Acquired
Immune Deficiency Syndrome) has been updated within the last eight years. A positive human immunodeficiency virus (HIV) test
must be accompanied by any of 26 opportunistic infections (infections that take advantage of a suppressed immune system).
THE VIRUS, AN INNOCENT BYSTANDER
Any entity that has the ability to replicate
uncontrollably under favorable condition is said to have viral characteristics. As an illustration, a stagnant stream
is known to breed mosquitoes. The proliferation of mosquitoes will continue as long as stagnation exists. This type of situation
is said to be viral and can be stopped not with insecticides but by changing the stream flow from stagnation to free flowing.
The use of insecticides helps the mosquitoes develop an immunity which allows them to survive. These characteristics are applicable
to viruses, too, as they can develop resistant strains to elude antimicrobial agents that protect the host’s internal
environment and immune system and that normally make viral contact infective.
Any virus in the body, that
proliferates when the immune system is deficient is a “human immunodeficient virus”. It’s a lie to call
or isolate just one virus as the HIV virus because the human body is a harbinger of millions of viruses. When the immune system
is deficient, a medical tsunami ensures. Primary, secondary and tertiary disorders spring up. A virus is a needle in a haystack
in this scenario. The acquired immunity deficiency syndrome is the disease of the 20th century. It is primarily a cascade
of immune dysfunctions that had nothing to do with a virus. Somebody decided to tag an arbitrary virus and associate it with
these immune dysfunctions for financial reason. Till date the medical community has fraudulently refused to understand the
immune dysfunctions that made this arbitrary virus opportunistic, while trillions of dollars have been spend to understand
this virus. What a shame!
The viruses, microbes, and parasites associated with the liver did not come
directly from nature but as mutations from the use of synthetic drugs. As we violate the body with antimicrobial agents, we
will end up with hepatitis Z or until we no longer have letters to alphabetize illness. This book represents a paradigm shift
that harnesses the innate healing abilities of the human body. Viruses will not be our emphasis. The healing process will
correct malnutrition, enforce detoxification, and eradicate all liver antigens and toxic wastes that interfere with health.
Ironically, we will have succeeded in shifting your emphasis from the care of the disease to the healing of your body. This
is accomplished through comprehensive non-toxic natural remedies.
All viruses bind to their hosts
and introduce their genetic material into the host cell as part of their replication cycle. This genetic material contains
basic 'instructions' of how to produce more copies of these viruses, hijacking the body's normal production machinery to serve
the needs of the virus. The host cell will carry out these instructions and produce additional copies of the virus, leading
to more and more cells becoming infected. Some types of viruses insert their genes into the host's genome, but do not actually
enter the cell. Others penetrate the cell membrane disguised as protein molecules and enter the cell.
There are two main types of virus infection: lytic and lysogenic.
The origin of viruses
is poorly understood, but most virologists (people who study viruses) agree that each virus got started by copying a few useful
genes from their host cells. Viruses are ignorant of any patent or copyright laws, they just make a copy of what they find
useful in the host's genome and move on. Often that useful gene is intimately involved in the host's reproduction, food gathering,
cell communication or other essential function of the cell. The number of viral immune evasion strategies has increased dramatically
in recent years. Over the generations viruses mutate their stolen genes and when a particularly useful mutation comes along,
the virus will use it to further its own survival, usually to the detriment of its host. As the years and generations go by,
these viruses can even switch over to other species, find new genes to copy and then continue evolving in their own selfish
way. Therefore, viruses were using recombinant genetics long before man had thought of it. How do new strains come about?
They evolve! Molecular evolution (the evolution of molecules) is a fascinating area of evolution and of prime concern to any
scientist wanting to understand viruses and how they spread. All genetic material can mutate, that is change its nucleic acids.
The mutations are random, but their selection is not. "Selection" is another word for how well they survive and
reproduce. Selection ensures that the mutations that increase a virus' ability to survive and reproduce will be represented
in even greater numbers in the next generation. Mutations are the "fuel" for evolution because they provide the
genetic variation on which selection acts. This is simply Darwin's old theory of evolution by means of natural selection,
but on a microscopic scale. So, the immune system will protect us from becoming reinfected with the same virus (from, say
a family member who caught it from you in the first place), but we will not be protected from a new strain.
Shortly
after inserting its DNA, viruses of the lytic cycle quickly produce more viruses, burst from the cell and infect more cells.
Lysogenic viruses integrate their DNA into the DNA of the host cell and may live in the body for many years before
responding to a trigger. The virus reproduces as the cell does and does not inflict bodily harm until it is triggered. The
trigger releases the DNA from that of the host and employs it to create new viruses. HIV is a lysogenic infection. Some scientists
believe that if they find the origin of its trigger, they will be able to stop the virus from ever reproducing throughout
the body.
An oncovirus is a virus associated with cancer.Oncoviruses comes in two different forms: viruses with
a DNA genome, such as adenovirus, and viruses with an RNA genome, like the Human T-cell Leukemia viruses and several viruses
known to be common in cats, mice and chickens. The oncogenic mechanism is either to insert additional oncogenic genes in the
host DNA, or to enhance already existing oncogenic genes in the genome.
Classification of viruses: Retroviruses
- A class of viruses that can create double-stranded DNA copies of their RNA genomes. These copies of its genome can be integrated
into the chromosomes of host cells. Human immunodeficiency virus (HIV) is a retrovirus. It is not only DNA viruses that are
associated with cancers some RNA viruses have also been associated such as the Hepatitis C Virus as well as Human T cell leukaemia
virus-1 (HTLV-1)
Adenoviruses - A class of viruses with double-stranded DNA genomes that cause respiratory,
intestinal, and eye infections in humans. The virus that causes the common cold is an adenovirus. Adeno-associated viruses
- A class of small, single-stranded DNA viruses that can insert their genetic material at a specific site on chromosome 19.
Herpes simplex viruses - A class of double-stranded DNA viruses that infect a particular cell type, neurons. Herpes simplex
virus type 1 is a common human pathogen that causes cold sore
The genetic material in retroviruses
is in the form of RNA molecules, while the genetic material of their hosts is in the form of DNA. When a retrovirus infects
a host cell, it will introduce its RNA together with some enzymes, namely reverse transcriptase and integrase, into the cell.
This RNA molecule from the retrovirus must produce a DNA copy from its RNA molecule before it can be integrated into the genetic
material of the host cell. The process of producing a DNA copy from an RNA molecule is termed reverse transcription. It is
carried out by one of the enzymes carried in the virus, called reverse transcriptase. After this DNA copy is produced and
is free in the nucleus of the host cell, it must be incorporated into the genome of the host cell. That is, it must be inserted
into the large DNA molecules in the cell (the chromosomes). This process is done by another enzyme carried in the virus called
integrase.
Now that the genetic material of the virus has been inserted, it can be said that the host cell has
been modified to contain new genes. If this host cell divides later, its descendants will all contain the new genes. Sometimes
the genes of the retrovirus do not express their information immediately.
A virus is a lifeless, innocent and
defenseless entity when independent, but alive like under the right conditions. We create these conditions by our violation
of natural laws. It is an opportunistic organism that is neither dead nor alive. They are thought to predate mankind. Unlike
human cells and bacteria, they are unable to eat, grow, and reproduce. They lack the chemical equipment, or enzymes, needed
to carry out chemical reactions for life. Viruses only carry information needed to decode their genetic instructions. Therefore,
a virus must have a weak host cell, like a human, plant, or animal cell, in which to live and make more viruses.
Viruses in gene therapy
Gene therapy is a technique for correcting defective
genes responsible for disease development. Researchers may use one of several approaches for correcting faulty genes:
How does gene therapy work?
In most gene therapy studies, a "normal"
gene is inserted into the genome to replace an "abnormal," disease-causing gene. A carrier molecule called a vector
must be used to deliver the therapeutic gene to the patient's target cells. Currently, the most common vector is a virus that
has been genetically altered to carry normal human DNA. Viruses have evolved a way of encapsulating and delivering their genes
to human cells in a pathogenic manner. Scientists have tried to take advantage of this capability and manipulate the virus
genome to remove disease-causing genes and insert therapeutic genes.
Target cells such as the patient's
liver or lung cells are infected with the viral vector. The vector then unloads its genetic material containing the therapeutic
human gene into the target cell. The generation of a functional protein product from the therapeutic gene restores the target
cell to a normal state. See a diagram depicting this process.
One of the problems of gene therapy
using retroviruses is that the integrase enzyme can insert the genetic material of the virus into any arbitrary position in
the genome of the host; it randomly inserts the genetic material into a chromosome. If genetic material happens to be inserted
in the middle of one of the original genes of the host cell, this gene will be disrupted (insertional mutagenesis). If the
gene happens to be one regulating cell division, uncontrolled cell division (i.e., cancer) can occur. This problem has recently
begun to be addressed by utilizing zinc finger nucleases[4] or by including certain sequences such as the beta-globin locus
control region to direct the site of integration to specific chromosomal sites.
Gene therapy trials
using retroviral vectors to treat X-linked severe combined immunodeficiency (X-SCID) represent the most successful application
of gene therapy to date.Concerns about the safety of adenovirus vectors were raised after the 1999 death of Jesse Gelsinger
while participating in a gene therapy trial. Since then, work using adenovirus vectors has focused on genetically crippled
versions of the virus.
Virology is the study of viruses, their laboratory terminologies, and indices
that identify them. It identifies different stages of viral diseases and therapeutic interventions. Virology also involves
the study of blood serum tests that show the presence of viral antigens, viral antibodies, and the phase of viral multiplication
in the body.
Every day we are exposed
to different substances, some which are small enough to enter our body, bypass our primary defenses, and even find their way
into the bloodstream. Even with exposure to these substances, most of us do not become sick and are still able to perform
our daily activities. Some people even feel as if they have never been sick, and claim that
they are feeling great and healthy. Some may just feel a little feverish or develop fever spikes during the first exposure
to a substance, and afterward, feel fine. Thus, a question develops, why do these things occur?
We are talking here about disease transmission and immune response. The substances we
are referring to may well refer to those harmful organisms or pathogenic substances that are able to get
inside the body. For those who do not know, our body is equipped with a lot of defenses. Our skin, the liquid excreted through
the pores and openings, and some internal protective structures such as the lining of our intestines, are considered as the
primary defenses in our body.
When a harmful organism is able to bypass these defenses,
it is the role of our specialized cells to act. These cells look for foreign or invading substances and try to deal with them,
until they are accommodated by the body so as to not cause any problems afterwards. The presence of an antigen will alert
the body to mobilize, deal with the invading organism, and prevent it from affecting normal functioning. As long as this happens
we are said to be well because health is not the absence but containment of disease.
According
to Shé D'Montford, Shambhallah, from Australia ‘The human body "WILL HEAL"... If we get out of our
own way and allow it, it heals itself. It is our basic nature. Anybody who tells you other than that is trying to sell you
something. No matter what you have been told. Don't give up on yourself and don't buy into the lines like ... ‘oh well
you've had a good life'... 'at your age'... and the worst of all ...'there's nothing further I can do, I suggest you finalize
your affairs'... How dare anyone tell you to give up! So much in society combines to convince us of the propaganda that some
things never get better. It's up to you ... do you want to get better? Make things better? It is human nature to make things
better, evolve and grow.”
This site is intended to provide general information only and is not a substitute
for medical evaluation or treatment. All matters regarding health or a particular health situation should be supervised by
a licensed health care professional.The author and the publisher shall not be held responsible or liable for any harm or loss
allegedly arising, directly or indirectly from any information in this site